Order number AK1605-S 100 assays
The AKCELL GJB2 AK™PCR Mutation Screen Kit is designed to screen for mutations on the Gap junction beta-2 protein (GJB2), also known as connexin 26 (Cx26) gene in genomic DNA, commonly associated with prelingual hearing loss.
GJB2 Mutations and Cancer Gap junction beta-2 protein (GJB2), also known as connexin 26 (Cx26) — is a protein that in humans is encoded by the GJB2 gene. Defects in this gene lead to the most common form of congenital deafness in developed countries, called DFNB1 (also known as connexin 26 deafness or GJB2-related deafness).[1]
Equipment Compatible with ABI 7500 Real-Time Systems or equivalent.
Intended Use AKCELL’s GJB2 mutation screen reagents are provided for research use only (RUO).
1- Kenneson A, Van Naarden Braun K, Boyle C (2002). “GJB2 (connexin 26) variants and nonsyndromic sensorineural hearing loss: a HuGE review.”. Genet. Med. 4 (4): 258–74.
